Diseases which may be prevented or cured by means of therapeutic fasting and caloric restriction  
(experimental and clinical evidence: click to see scientific report)

» arthritis rheumatoid
» asthma
» cardiovascular diseases
» cholecystitis and gout
» chronic fatigue syndrome
» diabetes
» digestive system diseases
» epilepsy
» glomerulonephritis
» hypertension
» infections
» infertility
» Low immunity
» neurodegenerative disorders
» obesity
» ovarian tumors
» pancreatitis
» psoriasis
» psychiatric disorders
» respiratory system diseases
» skin disorders
» spinal column diseases
» thrombophlebitis
» tumours, cancer
» uterine fibroids
» Complications in fasting
» Safety of fating
» sarcoidosis
Anti-Aging Therapy
Fasting / low-calorie program on Adriatic Sea Coast
Intermittent calorie restriction delays prostate tumor detection and i
 
 Prostate cancer is the most frequently diagnosed cancer in men. Whereas chronic calorie restriction (CCR) delays prostate tumorigenesis in some rodent models, the impact of intermittent caloric restriction (ICR) has not been determined. Here, transgenic adenocarcinoma of the mouse prostate (TRAMP) mice were used to compare how ICR and CCR affected prostate cancer development. TRAMP mice were assigned to ad libitum (AL), ICR (2 wk 50% AL consumption followed by 2 wk pair feeding to AL consumption), and CCR (25% AL consumption) groups at 7 wk of age and followed until disease burden necessitated euthanasia or mice reached terminal endpoints (48 or 50 wk of age). Body weights fluctuated in response to calorie intake (P < 0.0001). ICR mice were older at tumor detection than AL (P = 0.0066) and CCR (P = 0.0416) mice. There was no difference for age of tumor detection between AL and CCR mice (P = 0.3960). Similar results were found for survival. Serum leptin, adiponectin, insulin, and IGF-I were all significantly different among the groups. These results indicate that the way in which calories are restricted impacts both time to tumor detection and survival in TRAMP mice, with ICR providing greater protective effect compared to CCR.

«« Back